Medicine Avg. $75

CPT 96365: IV Infusion, Initial, Up to 1 Hour

Intravenous infusion for therapy, prophylaxis, or diagnosis, initial, up to 1 hour. Used for the first hour of IV infusion of a drug or substance.

Why CPT 96365 Claims Get Denied

Claims billed under CPT 96365 are frequently denied or downcoded for the following reasons. Understanding these patterns helps your practice reduce denial rates and recover revenue faster.

Infusion time less than 16 minutes (does not meet threshold)

Missing drug HCPCS code or NDC

Bundled with chemotherapy administration

Prior authorization for the infused drug not obtained

Billing Tips for CPT 96365

Infusion must last at least 16 minutes to bill 96365. For infusions over 1 hour, add 96366 for each additional hour. Do not bill concurrently with hydration if same IV line. Bill the drug separately with J-code. Document start and stop times precisely.

Documentation Requirements

To support a clean claim for CPT 96365, your clinical documentation should include:

Provider order for the infusion

Drug name, dose, and rate

Start and stop times for the infusion

Monitoring notes during infusion

Patient response to treatment

NDC and lot number

Common Modifiers for CPT 96365

Modifier 59

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